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The Nikkei 225 index closed at 39,881.10 points in early trading, up 1.29%.Zhangjiakou Smart Grid Auto Equity Investment Fund was registered and established. The enterprise search APP shows that recently, Zhangjiakou Smart Grid Auto Equity Investment Fund Partnership (Limited Partnership) was established with a capital contribution of 301 million yuan. Its business scope includes: engaging in equity investment, investment management and asset management with private equity funds. Enterprise investigation shows that the company is jointly owned by Zhangjiakou Industrial Investment Holding Group Co., Ltd. and Zhangjiakou Nanshan Economic Development Zone Construction and Development Co., Ltd.The next "explosion point" of biomedicine may appear in Shenzhen. "China's pharmaceutical innovation ranks first in the second echelon in the world in terms of the quantitative indicators of R&D pipelines and listed new drugs." A few days ago, Song Ruilin, executive president of China Pharmaceutical Innovation Promotion Association, held the "Star of the Bay Area" biomedical source innovation conference in Shenzhen, and believed that China's pharmaceutical research and industrial development were entering a new stage of innovation. Chen Qiyu, vice president of China Pharmaceutical Innovation Promotion Association and executive director and co-CEO of Fosun International, said that Shenzhen has great advantages and development momentum in linking Greater Bay Area's urban development and AI technology. By leveraging the resources in the Bay Area and making good use of these advantages, it is possible to find a new fulcrum in the future biomedical R&D innovation track, and the next "explosion point" of biomedicine is likely to appear in Shenzhen.

Police in Xichang, Sichuan: A man who knocked down a pedestrian after drinking and driving killed three people and was detained.Treasury futures rose by 0.30%, the 30-year main contract rose by 0.30%, and the 30-year main contract rose by 0.30%, a record high. The 10-year main contract rose by 0.12%, the 5-year main contract rose by 0.05% and the 2-year main contract rose by 0.02%.Beijing Haidian Joy City will open on December 21st. According to WeChat official account news of "Beijing Haidian" WeChat, Haidian Joy City, the fourth joy city in Beijing, will open on December 21st. At present, many brands have come to an end, and the merchants in the venue have entered the preparations for opening. It is understood that Haidian Joy City is expected to introduce more than 280 brands.

The person in charge of public relations of Extreme Vietnam responded to the operating conditions, saying that the company had no money. Xu Jiye, the person in charge of public relations of Extreme Vietnam Automobile, responded to the financial difficulties of the company, saying that the company needed to find funds to survive because of lack of money. Xu Jiye stressed that he joined the company because he was optimistic about the products, and even bought one without receiving a salary, and recommended it to relatives and friends. He angrily refuted the remarks that the company's difficulties questioned the quality of products and said that he would continue to promote the cause of autonomous driving.Many places have started issuing coupons to help the consumption of catering and cultural tourism. With the arrival of the peak consumption season at the end of the year, Beijing, Changzhou, Jiangsu, Xi 'an and other places have started a new round of issuing coupons to support the consumption fields such as catering and cultural tourism. Shanghai "Lepin Shanghai" food and beverage coupons were distributed in the first batch in the third round, and all four coupons were arranged at a 30% discount. The first round of 40 million food and beverage coupons were collected within 15 minutes. Consumer vouchers cover many fields and are distributed in rolling stages to meet the needs of different consumers. The data shows that the role of consumer vouchers in stimulating consumption has steadily increased, effectively boosting consumer confidence and driving the recovery of related industries. Experts believe that consumer vouchers can produce a multiplier effect and promote economic activities. At the same time, it is necessary to strengthen supervision, prevent violations, introduce social capital to participate in the issuance of consumer vouchers, and form a diversified development model. (Securities Times)The negative spread of 10-year national debt between China and the United States has expanded to nearly 250BP, which is the largest in more than 22 years.